Vraylar (Cariprazine)

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Vraylar (cariprazine) is an effective atypical antipsychotic used to manage schizophrenia, bipolar I disorder, and as an adjunct for major depressive disorder. By targeting dopamine and serotonin receptors, it helps stabilize mood, reduce psychotic symptoms, and improve overall functioning.

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Description

Vraylar (generic name: cariprazine) is a prescription medication approved by the U.S. Food and Drug Administration (FDA) to treat certain mental health conditions. Belonging to the class of atypical antipsychotics, Vraylar is primarily used for:

  • Schizophrenia in adults

  • Bipolar I disorder (manic, mixed, or depressive episodes)

  • Adjunctive treatment of major depressive disorder (MDD) in adults

Vraylar works by balancing levels of dopamine and serotonin, two key neurotransmitters that influence mood, behavior, and thinking.


How Vraylar Works

Vraylar acts as a dopamine D2/D3 receptor partial agonist and a serotonin 5-HT1A partial agonist, while blocking serotonin 5-HT2A receptors. This mechanism helps regulate mood, reduce psychotic symptoms, and improve emotional stability.


Benefits of Vraylar (Cariprazine)

  • Reduces hallucinations and delusions in schizophrenia.

  • Stabilizes mood in bipolar I disorder.

  • Improves depressive symptoms when used alongside antidepressants in MDD.

  • Long half-life, which may reduce fluctuations in symptoms.

  • Lower risk of weight gain and sedation compared to some other antipsychotics.


Vraylar Dosage and Administration

  • Schizophrenia: 1.5 mg to 6 mg once daily.

  • Bipolar I disorder: 1.5 mg to 6 mg once daily, depending on response.

  • Adjunctive treatment in MDD: typically 1.5 mg to 3 mg once daily.

Additional information

Dosage

1.5 mg, 3 mg, 4.5 mg, 6 mg

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